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# VP, Biometrics & Data Science with a Biotech Firm – Boston, MA



Role Overview for VP, Biometrics & Data Science with a Biotech Firm – Boston, MA
JRG Partners is proud to represent a pioneering, clinical-stage biotechnology firm in their search for a visionary Vice President of Biometrics and Data Science. Located in the heart of Boston’s thriving life sciences ecosystem, our client is dedicated to developing transformative therapies for patients with severe and life-threatening diseases.
This is a rare opportunity to join a dynamic executive leadership team and build a world-class biometrics function from a strategic and tactical perspective. The successful candidate will be a key architect of the company’s clinical development strategy, shaping the future of its innovative pipeline through the rigorous application of statistical principles and cutting-edge data science methodologies.
As the VP, Biometrics & Data Science, you will provide enterprise-level leadership and strategic direction for all aspects of biostatistics, statistical programming, and data management across the entire clinical portfolio. You will be responsible for ensuring the highest standards of quality, integrity, and scientific rigor in the design, analysis, and reporting of clinical trials. This executive role demands a leader who can seamlessly blend deep technical expertise with strategic business acumen, capable of mentoring a high-performing team while influencing key decisions at the highest levels of the organization.
You will be the internal and external subject matter expert on all biostatistical matters, interacting with regulatory agencies, key opinion leaders, and corporate partners. This role is pivotal in translating complex data into actionable insights that will accelerate drug development, support successful regulatory submissions, and ultimately bring novel medicines to patients in need. If you are a strategic thinker with a passion for data-driven innovation and a proven track record of leadership in the biopharmaceutical industry, we invite you to explore this career-defining opportunity.
Key Responsibilities of VP, Biometrics & Data Science with a Biotech Firm – Boston, MA
The Vice President of Biometrics and Data Science will have a broad range of responsibilities, encompassing strategic leadership, functional management, and hands-on technical guidance. Your duties will be critical to the success of the company’s clinical programs.
Strategic & Technical Leadership

Develop and execute the overarching vision and long-term strategy for the Biometrics and Data Science function, ensuring alignment with corporate goals and clinical development plans.
Provide expert statistical leadership and guidance on all clinical development programs, from early-stage design to late-stage submission and post-marketing activities.
Serve as the primary statistical representative in high-level meetings with executive management, regulatory authorities (e.g., FDA, EMA), and external partners.
Oversee the design of innovative and efficient clinical trials, including the development of study protocols, statistical analysis plans (SAPs), and sample size calculations.
Drive the adoption of advanced statistical methods, adaptive designs, and data science techniques (e.g., machine learning, AI, real-world evidence analysis) to optimize clinical development.

Functional Management & Team Development

Build, lead, and mentor a high-performing team of biostatisticians, statistical programmers, and data managers.
Foster a culture of scientific excellence, collaboration, innovation, and continuous improvement within the department.
Manage departmental resources, including budget, headcount, and the selection and oversight of Contract Research Organizations (CROs) and other vendors.
Establish and maintain departmental SOPs, best practices, and standards to ensure the highest quality of deliverables and full compliance with regulatory requirements.
Set clear performance objectives, provide regular feedback, and support the professional growth and development of all team members.

Execution & Delivery

Assume ultimate accountability for all biometrics deliverables, including clinical study reports, integrated summaries of safety and efficacy (ISS/ISE), and statistical sections of regulatory submissions (e.g., INDs, NDAs, BLAs).
Ensure the integrity, quality, and accuracy of all clinical trial data and statistical analyses.
Oversee the development and validation of statistical programs for analysis datasets (e.g., ADaM), tables, listings, and figures (TLFs).
Guarantee that all functional activities are conducted in accordance with Good Clinical Practice (GCP), ICH guidelines, and other applicable global regulations.
Collaborate with Data Management to ensure the development of robust data collection systems and the implementation of effective data quality oversight plans.

Cross-Functional Collaboration

Work closely with leaders in Clinical Development, Clinical Operations, Regulatory Affairs, and Medical Affairs to ensure seamless integration of biometrics activities into overall program strategy.
Provide statistical expertise to support publication planning, manuscript development, and scientific presentations.
Partner with research and translational science teams to provide statistical input on biomarker development and translational data analysis.
Effectively communicate complex statistical concepts and results to diverse, non-statistical audiences, including senior management and external stakeholders.

Requirements for the VP, Biometrics & Data Science with a Biotech Firm – Boston, MA
The ideal candidate will be an accomplished biostatistician with extensive leadership experience and a deep understanding of the drug development process. Qualifications include:
Educational Background
A Ph.D. in Biostatistics, Statistics, or a closely related quantitative field is strongly preferred. An M.S. with an exceptional record of leadership and experience will be considered.
Professional Experience
A minimum of 15 years of progressive experience in the biotechnology or pharmaceutical industry, with at least 8-10 years in a leadership role managing biostatistics and programming teams.
Regulatory Expertise
Extensive experience with direct regulatory interactions (FDA, EMA) and a proven track record of successful NDA/BLA or other major regulatory submissions. Deep knowledge of the entire clinical development lifecycle, from Phase I through Phase IV.
Technical Proficiency

Expert-level knowledge of advanced statistical methodologies used in clinical trial design and analysis (e.g., survival analysis, longitudinal data analysis, Bayesian methods, adaptive designs).
Proficiency with statistical programming languages such as SAS and R.
Thorough understanding of CDISC standards, including SDTM and ADaM, and their implementation.
Demonstrated ability to ensure all statistical work is compliant with current FDA regulatory guidelines and ICH standards.

Leadership & Communication Skills

Demonstrated ability to build, lead, and inspire a high-performing technical team.
Exceptional strategic thinking, problem-solving, and decision-making capabilities.
Excellent verbal and written communication skills, with the ability to articulate complex statistical issues and solutions to both technical and non-technical audiences.
Strong interpersonal skills and a proven ability to collaborate effectively across a matrixed organization.
Experience managing CROs and external vendors, including contract negotiation and performance oversight.

Therapeutic Area Experience
Prior experience in specific therapeutic areas such as oncology, immunology, rare diseases, or neurology is highly desirable.
Benefits & Perks Offered
Our client is committed to attracting and retaining top talent by offering a highly competitive compensation and benefits package. This includes:
Competitive Compensation
A highly attractive base salary, annual performance-based bonus, and a significant equity package (stock options/RSUs).
Comprehensive Health & Wellness
Full medical, dental, and vision insurance for employees and their dependents, along with wellness programs and a flexible spending account (FSA).
Retirement Planning
A 401(k) retirement plan with a generous company match.
Work-Life Balance
A generous paid time off (PTO) policy, including vacation, sick days, and company holidays.
Professional Development
A substantial budget for continuing education, professional memberships, and attendance at key industry conferences.
Relocation Assistance
A comprehensive relocation package is available for the right candidate.
Inspiring Work Environment
The opportunity to work alongside a passionate and brilliant team in a collaborative, science-driven culture dedicated to making a difference in patients’ lives.
How to Apply
This is an exclusive search being conducted by JRG Partners. If you are a qualified leader with the expertise and passion to drive the biometrics and data science function at a leading-edge biotech company, we encourage you to apply. Your leadership will directly contribute to the development of groundbreaking therapies. To be considered for this exceptional opportunity, please submit your resume and a detailed cover letter outlining your relevant experience.
All applications are held in the strictest confidence. To apply for this exclusive opportunity, please submit your resume and cover letter through our Life Sciences & Biotechnology practice area portal. We look forward to reviewing your qualifications.