Role Overview for Chief Business Officer, Biosciences – South San Francisco, CA
JRG Partners is proud to partner with a pioneering, clinical-stage biosciences company at the forefront of developing transformative therapies for complex diseases. Located in the vibrant biotechnology hub of South San Francisco, our client is driven by a mission to translate cutting-edge scientific discoveries into life-changing medicines. We are seeking a dynamic, strategic, and results-oriented Chief Business Officer (CBO) to join their executive leadership team. This is a pivotal role that will shape the company’s future, drive its growth trajectory, and establish its position as a leader in the global biopharmaceutical landscape.
The Chief Business Officer will be the principal architect of the company’s corporate and business strategy. This individual will be responsible for all aspects of business development, corporate development, strategic planning, and commercialization strategy. Reporting directly to the Chief Executive Officer, the CBO will work in close collaboration with the executive team, including the heads of R&D, Finance, and Clinical Operations, to identify and execute on strategic initiatives that maximize shareholder value and advance the company’s mission. The ideal candidate is a seasoned biopharma executive with a profound understanding of the science, a robust network within the industry, and a proven track record of structuring and negotiating high-value, complex deals. This individual must be a visionary leader capable of navigating the complexities of the biotech market, from early-stage asset valuation to late-stage commercial partnerships and M&A activities. Your leadership will be instrumental in securing the strategic partnerships and financial resources necessary to bring novel therapies from the laboratory to patients in need.
Key Responsibilities of Chief Business Officer, Biosciences – South San Francisco, CA
The CBO will have a broad and impactful remit, overseeing the strategic and commercial direction of the company. Key responsibilities are comprehensive and require a blend of scientific acumen, financial expertise, and strategic negotiation skills.
Corporate Strategy & Leadership:
- Serve as a key member of the executive leadership team, contributing to the overall corporate strategy, long-range planning, and operational execution.
- Lead the annual strategic planning process, translating scientific and clinical objectives into a coherent and actionable corporate and business development strategy.
- Provide insightful analysis of the competitive landscape, market trends, and emerging technologies to identify strategic opportunities and mitigate potential risks.
- Collaborate with the CEO and CFO on fundraising activities, including venture capital rounds, public offerings, and other financing vehicles, preparing compelling business cases and presentations for investors.
Business Development & Licensing:
- Lead all business development activities, including the identification, evaluation, and execution of strategic partnerships, collaborations, and licensing agreements (in-licensing and out-licensing).
- Direct the search and evaluation process for new assets and technologies that align with the company’s strategic focus, conducting thorough due diligence in partnership with R&D, clinical, and legal teams.
- Structure, negotiate, and close complex deals that enhance the company’s pipeline, capabilities, and market position.
- Build and maintain a strong network of contacts across the biopharmaceutical industry, academia, and the investment community to ensure a robust pipeline of opportunities.
Commercial Strategy & Alliance Management:
- Develop and oversee the pre-commercial and commercialization strategy for the company’s product pipeline, including market analysis, product positioning, pricing, and reimbursement strategies.
- Build and lead a high-performing alliance management function to ensure the success of existing and future partnerships, fostering strong relationships and ensuring all parties meet their obligations.
- Provide commercial input into clinical development plans to ensure programs are designed to meet market needs and support a strong value proposition for payers and providers.
- Oversee market intelligence activities to inform strategic decisions and maintain a deep understanding of the evolving therapeutic landscape.
Requirements for the Chief Business Officer, Biosciences – South San Francisco, CA
The successful candidate will be a proven leader with extensive experience in the biopharmaceutical industry. A combination of advanced scientific knowledge and demonstrated business success is essential.
Educational & Professional Experience:
- Advanced degree (PhD, MD, or MBA) is strongly preferred. A combination of a scientific degree and an MBA is ideal.
- A minimum of 15-20 years of progressive experience in the biotechnology or pharmaceutical industry, with at least 10 years in a senior leadership role in business development, corporate strategy, or a related function.
- An extensive and verifiable track record of successfully leading and closing a wide range of strategic transactions, including M&A, licensing agreements, joint ventures, and research collaborations.
- Experience in a small to mid-sized, high-growth biotech environment is highly desirable.
- Deep experience across multiple therapeutic areas is beneficial, with specific expertise in the company’s core scientific areas being a significant plus.
Skills & Competencies:
Strategic Vision
Ability to think strategically and creatively, to anticipate future trends and to translate vision into actionable, value-creating plans.
Negotiation & Deal-Making
World-class negotiation skills with the ability to structure and execute deals that are strategically and financially sound.
Leadership & Influence
Proven ability to lead, influence, and build consensus among a diverse group of stakeholders, including the board of directors, executive peers, scientific teams, and external partners.
Scientific Acumen
Strong understanding of the drug discovery and development process, from preclinical research through clinical trials and regulatory approval.
Financial Acumen
Sophisticated understanding of financial modeling, valuation, and deal structuring.
Communication
Exceptional written, verbal, and presentation skills, with the ability to articulate complex scientific and business concepts to a wide range of audiences.
Industry Knowledge
Deep understanding of the global biopharmaceutical landscape and trends, as highlighted by organizations like the Biotechnology Innovation Organization (BIO).
Benefits & Perks Offered
Our client is committed to attracting and retaining top-tier talent by offering a highly competitive and comprehensive compensation and benefits package. As a key member of the executive team, you can expect:
Competitive Compensation
A highly competitive base salary, annual performance-based bonus, and significant equity participation (stock options/RSUs).
Comprehensive Health & Wellness
Premium medical, dental, and vision insurance for you and your dependents, along with wellness programs and a health savings account (HSA).
Retirement Planning
A robust 401(k) plan with a generous company match to help you plan for your future.
Work-Life Balance
A generous paid time off (PTO) policy, including vacation, sick leave, and company holidays, to support a healthy work-life integration.
Professional Development
Support for continued learning, executive coaching, and attendance at key industry conferences to foster your professional growth.
Relocation Assistance
A comprehensive relocation package is available for the ideal candidate if required.
How to Apply
JRG Partners is exclusively managing this executive search. If you are a visionary business leader with a passion for science and a track record of driving growth in the biosciences sector, we encourage you to apply. To be considered for this career-defining opportunity, please submit your resume and a cover letter detailing your relevant experience and strategic accomplishments.
For more information about our expertise in this sector and to submit your application, please visit our Top Biosciences Executive Recruiters Practice page. We look forward to reviewing your qualifications and discussing how you can make a transformative impact with our client.

