JRG Partners is exclusively representing a pioneering, patient-centric biopharmaceutical organization based in the heart of the Cambridge, MA biotech ecosystem. Our client is at the forefront of developing novel therapeutics for challenging diseases, with a robust and promising pipeline. We are seeking a transformative, strategic, and visionary leader to join their executive team as the Executive Vice President (EVP), Head of Biometrics and Clinical Data. This is a career-defining opportunity to build and lead a world-class function, directly influencing the trajectory of groundbreaking medicines from early development through global commercialization.
As the EVP, you will be the ultimate authority for all biostatistics, statistical programming, and clinical data management activities across the organization. You will not only provide operational oversight but also set the strategic vision for how data is collected, managed, analyzed, and interpreted. This role requires a leader who can seamlessly blend deep scientific and statistical expertise with executive-level business acumen, influencing key decisions across the R&D leadership team and the broader company. You will be instrumental in shaping the company’s development strategies, interacting with regulatory bodies, and ensuring the absolute integrity and quality of the clinical data that forms the bedrock of their scientific and commercial success.
Role Overview for EVP, Head of Biometrics & Clinical Data with a Biopharma Firm – Cambridge, MA
The EVP, Head of Biometrics & Clinical Data is a paramount leadership position responsible for the strategic direction and operational execution of the entire biometrics and data management function. Reporting directly to the Chief Medical Officer, you will serve as a key member of the Research & Development Leadership Team. Your primary objective is to build and cultivate a high-performing, innovative organization that delivers exceptional quality and efficiency in support of the company’s full clinical development portfolio.
This executive will be accountable for ensuring that all clinical programs are supported by robust statistical designs, state-of-the-art data management practices, and flawless analytical execution. You will champion a culture of quality, compliance, and scientific rigor, ensuring that all functional activities adhere to global regulatory standards. Beyond functional leadership, you will be a strategic partner to colleagues in Clinical Development, Clinical Operations, Regulatory Affairs, and Pharmacovigilance, providing critical statistical insights that shape trial designs, development pathways, and regulatory strategies. Your leadership will be crucial in navigating the complexities of global drug development and bringing new therapies to patients in need.
Key Responsibilities of EVP, Head of Biometrics & Clinical Data with a Biopharma Firm – Cambridge, MA
Strategic Vision & Leadership
Develop, articulate, and implement a long-range strategic vision for the Biometrics and Clinical Data organization that aligns with the company’s overall R&D and corporate objectives. Drive innovation and continuous improvement across the function.
Functional Accountability
Provide executive oversight for all biostatistics, statistical programming, and clinical data management activities across all phases of clinical development (Phase I-IV). Ensure timely and high-quality deliverables for clinical trial protocols, statistical analysis plans (SAPs), clinical study reports (CSRs), and regulatory submission documents.
Team Development & Mentorship
Recruit, develop, and retain a world-class team of leaders and individual contributors. Foster a collaborative, inclusive, and high-performance culture. Provide mentorship and career development opportunities for staff at all levels.
Regulatory Strategy & Interaction
Serve as the lead biometrics representative in key interactions with global health authorities, including the FDA, EMA, and others. Lead the statistical strategy and contributions for major regulatory submissions (e.g., INDs, CTAs, NDAs, BLAs, MAAs) and be accountable for their statistical integrity.
Technical & Scientific Excellence
Ensure the application of sound, innovative, and efficient statistical methodologies in clinical trial design, analysis, and interpretation. Stay abreast of cutting-edge statistical methods, data science techniques, and industry best practices to enhance the company’s capabilities.
Data Integrity & Compliance
Uphold the highest standards of data quality and integrity. Ensure that all functional processes and systems are fully compliant with Good Clinical Practice (GCP), ICH guidelines, and other applicable global regulations.
Process & Technology Innovation
Drive the evaluation and implementation of new technologies, systems, and processes to increase efficiency, quality, and insight generation. Champion the adoption of industry data standards, such as CDISC (SDTM, ADaM), across the portfolio.
Cross-Functional Collaboration
Act as a key strategic partner to other leaders within R&D and the broader organization. Provide expert statistical consultation to inform clinical development plans, go/no-go decisions, and overall portfolio strategy.
Budget & Resource Management
Develop and manage the departmental budget, ensuring optimal allocation of resources (both internal and external) to meet portfolio demands. Oversee the selection and management of CROs and other vendors providing biometrics and data management services.
Requirements for the EVP, Head of Biometrics & Clinical Data with a Biopharma Firm – Cambridge, MA
Educational Background
A Ph.D. or equivalent doctoral degree in Biostatistics, Statistics, or a closely related quantitative discipline is strongly preferred. An M.S. with extensive, relevant industry experience will be considered.
Executive Experience
A minimum of 15-20 years of progressive experience in the biopharmaceutical industry, with at least 10 years in significant leadership roles overseeing biostatistics, statistical programming, and/or clinical data management functions.
Regulatory Mastery
Deep, hands-on experience with global regulatory submissions (NDA/BLA/MAA) is essential. Must have a proven track record of successfully representing a company and its statistical strategies before the FDA and other major health authorities.
Leadership Acumen
Demonstrated ability to build, lead, and inspire large, multi-disciplinary teams. A history of attracting and developing top talent and fostering a culture of excellence and accountability.
Strategic Thinking
Exceptional ability to think strategically and translate broad corporate goals into actionable functional plans. Must be able to anticipate future trends and challenges in the biometrics landscape.
Scientific Expertise
Broad and deep knowledge of advanced statistical principles and their application to all phases of clinical drug development. Experience across multiple therapeutic areas is highly desirable, with a preference for oncology, immunology, neurology, or rare diseases.
Communication Skills
Outstanding written and verbal communication skills. The ability to convey complex statistical concepts clearly and persuasively to a variety of audiences, from technical experts to executive leadership and board members.
Influence & Collaboration
Proven ability to operate effectively in a matrixed environment, build strong cross-functional relationships, and influence decision-making at the highest levels of an organization.
Benefits & Perks Offered
Our client is committed to investing in their employees and offers a highly competitive and comprehensive rewards package designed to attract and retain top executive talent, including:
Executive Compensation
A highly competitive base salary, annual performance-based bonus, and a significant long-term incentive package (stock options/equity) that reflects the seniority and impact of the role.
Comprehensive Health & Wellness
Premium medical, dental, and vision insurance plans for you and your eligible dependents, along with wellness programs and resources.
Retirement Savings
A robust 401(k) retirement plan with a generous company match to help you plan for your future.
Work-Life Balance
A generous paid time off (PTO) policy, paid company holidays, and comprehensive parental leave programs.
Relocation Support
A comprehensive relocation package is available for the ideal candidate and their family.
Professional Growth
A strong commitment to professional development, including support for attending key industry conferences, continuing education, and executive coaching.
Impactful Culture
The opportunity to work in a dynamic, science-driven, and collaborative environment where your contributions will have a direct and meaningful impact on patients’ lives.
How to Apply
JRG Partners is proud to be the exclusive recruitment partner for this confidential search. We are seeking a transformative leader who is ready to shape the future of clinical data and biometrics at a truly innovative company. If you possess the requisite experience, strategic mindset, and passion for science, we strongly encourage you to apply.
To be considered for this pivotal role, please submit your curriculum vitae and a cover letter detailing your qualifications and leadership philosophy. All inquiries and applications will be handled with the utmost confidentiality.
