Role Overview for Partner, Life Sciences VC with a Venture Capital Firm – Boston, MA

JRG Partners is proud to represent a premier, thesis-driven venture capital firm at the forefront of healthcare innovation. Our client, a distinguished leader in the investment community, is seeking to appoint a Partner to join their Life Sciences investment team in their Boston, MA office. This is a rare and exceptional opportunity for a visionary leader with a profound scientific background and a proven investment track record to shape the future of medicine.

The new Partner will play a pivotal role in defining and executing the firm’s investment strategy across the life sciences spectrum, including therapeutics, diagnostics, medical devices, and digital health. Operating from the heart of the world’s most vibrant biotechnology hub, you will leverage your deep scientific expertise and extensive network to identify, invest in, and nurture the next generation of transformative companies poised to solve critical unmet medical needs. This role is not merely about capital allocation; it is about building enduring companies.

You will serve as a strategic advisor, a board member, and a mentor to visionary founders, guiding them from scientific discovery to clinical validation and commercial success. The ideal candidate is a strategic thinker, a collaborative partner, and a passionate advocate for innovation, possessing the unique ability to bridge the worlds of science and business. You will be a key member of the firm’s senior leadership, contributing to its culture, its reputation, and its continued success in generating top-tier returns for its Limited Partners while making a tangible impact on human health.

This position demands a unique blend of scientific rigor, financial acumen, and entrepreneurial spirit. You will be tasked with leading all aspects of the investment lifecycle, from sourcing and diligence to deal execution and portfolio management. Your contributions will directly influence the firm’s portfolio construction and thematic focus areas. Success in this role requires not only identifying groundbreaking science but also recognizing the potential for commercial viability and building conviction around leadership teams. You will be joining a dynamic, intellectually curious, and highly collaborative team that values diverse perspectives and a shared commitment to excellence. This is a career-defining role for an individual eager to operate at the highest level of venture capital and leave a lasting legacy on the healthcare landscape.

Key Responsibilities of Partner, Life Sciences VC with a Venture Capital Firm – Boston, MA

The Partner’s responsibilities are comprehensive, spanning the full venture capital lifecycle. You will be a driving force within the partnership, expected to operate with a high degree of autonomy while fostering a collaborative and transparent team environment. Your core duties will include:

Deal Sourcing and Pipeline Development

• Proactively identify and source high-potential investment opportunities in the life sciences sector, with a focus on therapeutics, biotechnology, and related healthcare technologies.
• Cultivate and maintain a robust network of relationships with entrepreneurs, academic institutions, research centers, key opinion leaders (KOLs), corporate venture groups, and other venture capitalists to ensure a consistent flow of high-quality deal opportunities.
• Represent the firm at major industry conferences, scientific meetings, and networking events to build brand visibility and establish yourself as a thought leader in the space.

Due Diligence and Investment Execution

• Lead and manage all phases of the due diligence process for potential investments, including in-depth evaluation of the science, technology, clinical development path, intellectual property landscape, market opportunity, and competitive environment.
• Assemble and manage teams of external experts and consultants to validate key assumptions and assess risks.
• Conduct thorough financial analysis, including building valuation models, analyzing capitalization tables, and assessing potential returns.
• Structure, negotiate, and execute complex investment transactions, including crafting term sheets and definitive legal documentation.
• Prepare and present comprehensive investment memoranda and deliver compelling presentations to the firm’s investment committee, articulating a clear and data-driven investment thesis.

Portfolio Company Management and Value Creation

• Serve as an active and engaged member of the Board of Directors for multiple portfolio companies, providing strategic guidance and hands-on support.
• Act as a trusted partner to management teams, assisting with critical strategic decisions related to R&D, clinical strategy, regulatory affairs, business development, and corporate finance.
• Leverage your network to help portfolio companies recruit key executives and scientific advisors, forge strategic partnerships, and secure follow-on financing.
• Monitor company performance, track key milestones, and provide regular updates to the partnership.
• Identify and facilitate exit opportunities, including M&A and IPOs, to maximize returns for the fund.

Firm Building and Ecosystem Engagement

• Contribute significantly to the firm’s overall investment strategy, culture, and long-term vision.
• Mentor and develop junior members of the investment team, fostering a culture of intellectual curiosity, analytical rigor, and professional growth.
• Actively participate in the firm’s fundraising activities, including preparing marketing materials and meeting with prospective and existing Limited Partners (LPs).
• Enhance the firm’s reputation as a leading life sciences investor through thought leadership activities such as publishing articles, speaking at conferences, and engaging with the broader innovation ecosystem.

Requirements for the Partner, Life Sciences VC with a Venture Capital Firm – Boston, MA

The ideal candidate will be a seasoned professional with a deep passion for science and a demonstrated ability to identify and support world-class life sciences companies. We are seeking an individual who combines exceptional intellectual horsepower with unimpeachable integrity and outstanding interpersonal skills. Specific qualifications include:

Educational Background

An advanced degree in life sciences (MD, PhD, or MD/PhD) is required. An MBA or equivalent business experience is highly desirable and considered a significant asset.

Professional Experience

A minimum of 12-15 years of relevant experience in the life sciences industry. This must include significant, direct venture capital investing experience at a reputable firm, ideally with a progression to a Principal or Partner level. Experience in biopharma business development, corporate venture, or top-tier management consulting with a healthcare focus can be complementary.

Investment Acumen

A proven, demonstrable track record of sourcing, leading, managing, and exiting successful life sciences investments. You must be able to articulate your investment thesis and the role you played in the success of your portfolio companies.

Scientific and Clinical Expertise

A sophisticated and deep understanding of the life sciences landscape, including current and emerging therapeutic modalities, drug discovery and development processes, and clinical trial design. Expertise in areas such as oncology, immunology, neurology, genetic medicine, or rare diseases is particularly valued.

Extensive Network

A vast and active personal network that spans the Boston/Cambridge biotech ecosystem and beyond, including entrepreneurs, scientists, clinicians, executives, and fellow investors.

Leadership and Board Presence

Proven experience serving on company boards and a demonstrated ability to command respect and provide insightful, strategic counsel to C-level executives. You must possess strong leadership qualities, executive presence, and the ability to influence and build consensus.

Financial and Transactional Skills

Strong financial modeling, valuation, and analytical skills. Expertise in structuring and negotiating venture financing rounds and familiarity with all aspects of deal documentation.

Personal Attributes

High emotional intelligence, a collaborative and team-oriented mindset, insatiable curiosity, a strong work ethic, and unwavering ethical standards. You must be an exceptional communicator, capable of conveying complex scientific and financial concepts to diverse audiences with clarity and conviction.

Benefits & Perks Offered

Our client is committed to attracting and retaining top-tier talent by offering a highly competitive and comprehensive compensation and benefits package. As a key member of the partnership, you will be rewarded for your contributions to the firm’s success.

Highly Competitive Compensation

A compelling package that includes a significant base salary, an annual performance-based bonus, and a substantial carried interest allocation in the firm’s funds, providing a direct stake in the success of your investments.

Comprehensive Health and Wellness

Premier medical, dental, and vision insurance plans for you and your eligible dependents. The package includes access to top-tier wellness programs, mental health resources, and a flexible spending account (FSA).

Retirement Planning

A robust 401(k) retirement plan with a generous company match to help you build long-term financial security.

Generous Time Off

A flexible and generous paid time off (PTO) policy, including vacation, sick leave, and company holidays, to ensure a healthy work-life balance.

Parental Leave

A supportive and comprehensive paid parental leave policy for all new parents.

Professional Development

A dedicated budget for continuous learning, including attendance at industry conferences, specialized training programs, and relevant coursework to keep you at the cutting edge of science and business.

Modern Workspace

A state-of-the-art office located in the heart of Boston’s innovation district, designed to foster collaboration and creativity.

Impactful Work

The unparalleled opportunity to work alongside brilliant minds, fund groundbreaking science, and build companies that will fundamentally change the practice of medicine and improve patients’ lives.

How to Apply

JRG Partners is leading the exclusive search for this Partner position. We are committed to a confidential, thorough, and efficient recruitment process. If you possess the requisite experience, scientific depth, and leadership qualities to excel in this role, we encourage you to apply.

To be considered, please submit your curriculum vitae and a cover letter outlining your investment philosophy and relevant experience. All applications will be treated with the strictest confidence. Our team will review all submissions and contact qualified candidates directly to schedule an initial discussion.

JRG Partners specializes in placing elite talent within the investment management sector. To learn more about our expertise and other opportunities, please visit our Venture Capital & Private Equity practice area page.

Our client is an equal opportunity employer. They celebrate diversity and are committed to creating an inclusive environment for all employees. All employment is decided on the basis of qualifications, merit, and business need.