Role Overview for Chief Development Operations Officer with a Mid-Size Pharma – San Francisco, CA
JRG Partners is proud to partner with a dynamic, patient-focused, mid-size pharmaceutical company in their search for a visionary Chief Development Operations Officer (CDOO). Based in the vibrant biotech hub of San Francisco, CA, this is a pivotal executive leadership role reporting directly to the Chief Medical Officer. The successful candidate will be instrumental in shaping the future of the company by providing strategic and operational leadership across all facets of clinical development operations.
This is a unique opportunity to join a company at a critical growth stage, with a promising pipeline of innovative therapies. The CDOO will be responsible for building and scaling a world-class development operations function, ensuring the efficient and compliant execution of all clinical trials from Phase I through post-marketing. You will be the driving force behind operational excellence, translating scientific strategy into actionable development plans and ultimately delivering life-changing medicines to patients in need. We are seeking a seasoned leader with a proven track record of success in the pharmaceutical industry, who is passionate about science, leadership, and making a tangible impact on human health. This role demands a strategic thinker with a hands-on approach, capable of navigating the complexities of global drug development while fostering a culture of collaboration, innovation, and urgency.
Key Responsibilities of Chief Development Operations Officer with a Mid-Size Pharma – San Francisco, CA
The Chief Development Operations Officer will have a broad range of responsibilities, encompassing strategic oversight, operational execution, and team leadership. Key duties include:
Strategic Leadership & Planning
Collaborate with the executive team to define and execute the company’s clinical development strategy. Provide strategic input on clinical development plans, study designs, timelines, and budgets to ensure alignment with corporate goals.
Operational Excellence
Assume full accountability for the oversight and execution of all clinical development operations activities, including Clinical Operations, Data Management, Biostatistics, Clinical Pharmacology, and Pharmacovigilance. Ensure all clinical trials are conducted on time, within budget, and to the highest quality standards.
Regulatory Compliance
Guarantee that all clinical development activities are conducted in strict adherence to global regulatory requirements, including Good Clinical Practice (GCP), ICH guidelines, and other applicable regulations. Oversee the preparation and review of clinical sections of regulatory submissions (e.g., INDs, NDAs, BLAs, MAAs).
Team Leadership & Development
Lead, mentor, and develop a high-performing development operations team. Foster a positive and collaborative team culture that promotes accountability, innovation, and continuous improvement. Attract and retain top talent to build a scalable and effective organization.
Vendor and CRO Management
Lead the selection, management, and oversight of Contract Research Organizations (CROs), central labs, and other clinical vendors. Establish strong partnerships and implement robust oversight plans to ensure vendor performance and quality.
Financial Management
Develop, manage, and oversee the development operations budget, ensuring optimal allocation of resources. Provide accurate forecasting and tracking of clinical trial costs and resource needs.
Cross-Functional Collaboration
Serve as a key leader within the organization, fostering strong collaborative relationships with R&D, Regulatory Affairs, Medical Affairs, Commercial, and Finance teams to ensure seamless program execution.
Process Improvement
Drive the implementation of best practices, innovative technologies, and streamlined processes within development operations to enhance efficiency, quality, and speed. Champion a mindset of continuous improvement across the function.
Requirements for the Chief Development Operations Officer with a Mid-Size Pharma – San Francisco, CA
The ideal candidate will be a highly experienced and accomplished leader with a deep understanding of the drug development process. Qualifications include:
Educational Background
An advanced degree (MD, PhD, or PharmD) is strongly preferred. A Bachelor’s degree in a life science discipline is required.
Professional Experience
A minimum of 15-20 years of progressive experience in the pharmaceutical or biotechnology industry, with at least 10 years in a senior leadership role overseeing clinical development operations.
Proven Track Record
Demonstrated success in leading and managing global clinical development programs from early-stage through to regulatory approval and commercialization. Experience with successful NDA/BLA submissions is essential.
Leadership Skills
Exceptional leadership, management, and mentoring skills with a proven ability to build and lead high-performing, multi-disciplinary teams. A collaborative leadership style with the ability to influence and align stakeholders across the organization.
Regulatory Expertise
In-depth knowledge of global regulatory requirements, ICH guidelines, and GCP. Extensive experience interacting with health authorities (e.g., FDA, EMA).
Strategic & Operational Acumen
Strong strategic thinking and problem-solving skills, with the ability to translate corporate strategy into operational reality. Must be both a strategic leader and a hands-on operator.
Communication Skills
Outstanding written and verbal communication skills, with the ability to effectively present complex information to a wide range of audiences, including executive leadership and external partners.
Location
Ability to work on-site in the San Francisco Bay Area. Relocation assistance may be provided for the right candidate.
Benefits & Perks Offered
Our client is committed to attracting and retaining top talent by offering a highly competitive compensation and benefits package. As a key member of the executive team, you can expect:
Competitive Compensation
A highly competitive base salary, annual performance-based bonus, and a significant equity package (stock options/RSUs).
Comprehensive Health & Wellness
Premium medical, dental, and vision insurance for you and your dependents. Wellness programs and resources to support your physical and mental health.
Retirement Savings
A robust 401(k) plan with a generous company match to help you plan for your future.
Generous Time Off
A flexible and generous paid time off (PTO) policy, including vacation, sick leave, and company holidays.
Professional Development
A strong commitment to your professional growth with support for attending industry conferences, workshops, and continuing education.
Relocation Support
Comprehensive relocation assistance for qualified candidates moving to the San Francisco Bay Area.
Inspiring Work Environment
The opportunity to work alongside a passionate and dedicated team in a collaborative, science-driven culture.
How to Apply
If you are a visionary leader with the experience and passion to drive clinical development operations for a growing pharmaceutical company, we encourage you to apply for this exciting opportunity. This role represents a chance to make a profound impact on the lives of patients worldwide.
To be considered, please submit your resume and a cover letter detailing your qualifications and interest in the role. JRG Partners is a leader in executive recruitment for the pharmaceutical and biotech industries. To learn more about our focus and how we connect top talent with transformative companies, we invite you to explore our expertise in Life Sciences executive search. We look forward to reviewing your application.
