Role Overview for VP, Clinical Data Science with an Oncology Biotech – Raleigh, NC
JRG Partners is proud to partner with a pioneering, clinical-stage oncology biotechnology company at the forefront of developing next-generation cancer therapies. Based in the vibrant Research Triangle Park (RTP) area of Raleigh, NC, our client is driven by a singular mission: to transform the lives of cancer patients through scientific innovation and data-driven precision. They have built a robust pipeline of novel therapeutics and are now seeking a visionary and strategic leader to join their executive team as the Vice President of Clinical Data Science.
This is a transformative opportunity to build and lead a world-class clinical data science function from the ground up. The VP, Clinical Data Science will be the organization’s senior-most expert on the application of advanced analytics, biostatistics, and computational science to accelerate and de-risk the clinical development pipeline. You will be responsible for crafting and executing a comprehensive data strategy that leverages cutting-edge methodologies, including artificial intelligence (AI) and machine learning (ML), to optimize trial design, identify patient populations, discover biomarkers, and generate compelling evidence for regulatory submissions. As a key member of the clinical development leadership team, you will report directly to the Chief Medical Officer and will be instrumental in shaping the company’s long-term R&D strategy and culture of data-centric decision-making. We are looking for a passionate leader who combines deep technical expertise with a proven ability to inspire teams, collaborate across functions, and drive tangible impact in the fight against cancer.
Key Responsibilities of VP, Clinical Data Science with an Oncology Biotech – Raleigh, NC
The Vice President of Clinical Data Science will have a broad and impactful remit, overseeing all aspects of biostatistics, statistical programming, and clinical data management. Your leadership will be critical in translating complex data into actionable insights that guide our clinical programs forward.
Strategic Leadership and Vision
Develop, articulate, and implement a long-term vision and strategy for the Clinical Data Science function. Ensure this strategy is fully aligned with the company’s corporate objectives and the evolving landscape of oncology drug development. Champion the use of innovative data science approaches across the organization to create a sustainable competitive advantage.
Team Development and Mentorship
Recruit, lead, and develop a high-performing, multi-disciplinary team of biostatisticians, data scientists, and statistical programmers. Foster a collaborative, innovative, and inclusive culture that encourages scientific curiosity, professional growth, and a commitment to excellence. Provide strong mentorship and technical guidance to team members at all levels.
Advanced Analytics and Statistical Innovation
Provide expert oversight for all statistical aspects of clinical development, from study design and protocol development to data analysis and reporting. Drive the integration of advanced analytical techniques, including predictive modeling, machine learning algorithms, and Bayesian methods, to enhance trial efficiency, identify predictive biomarkers, and better understand disease biology.
Clinical Trial Design and Execution
Partner closely with Clinical Development, Clinical Operations, and Medical Affairs to design innovative and efficient clinical trials. Provide statistical leadership on adaptive designs, master protocols, and the integration of real-world evidence (RWE) to supplement traditional trial data. Ensure the statistical integrity of all clinical studies.
Data Strategy and Governance
Establish and enforce robust processes for data management, data quality, and data governance. Oversee the implementation and management of clinical data systems (e.g., EDC, CTMS) and ensure adherence to industry standards such as CDISC (SDTM, ADaM).
Regulatory Interaction and Submissions
Serve as the primary statistical representative in interactions with global regulatory agencies, including the FDA and EMA. Lead the preparation of the statistical components of regulatory submissions (e.g., INDs, NDAs, BLAs), ensuring they are of the highest quality and scientific rigor.
Cross-Functional Collaboration
Act as a key strategic partner to other leaders across R&D and the broader organization. Collaborate seamlessly with research, translational medicine, regulatory affairs, and commercial teams to ensure that data-driven insights inform all stages of the product lifecycle. Effectively communicate complex statistical concepts to non-statistical audiences.
External Engagement and Thought Leadership
Stay abreast of the latest advancements in data science, biostatistics, and oncology research by engaging with the external scientific community. Represent the company at major scientific conferences, foster collaborations with academic institutions and key opinion leaders, and contribute to publications in peer-reviewed journals. Ensure our work is informed by the latest guidance from organizations like the National Cancer Institute (NCI).
Requirements for the VP, Clinical Data Science with an Oncology Biotech – Raleigh, NC
We are seeking an accomplished and strategic leader with a deep passion for leveraging data to revolutionize cancer treatment. The ideal candidate will possess a unique blend of technical mastery, leadership acumen, and industry experience.
Required Qualifications:
Educational Background
PhD or equivalent doctoral degree in Biostatistics, Statistics, Data Science, Epidemiology, or a related quantitative field is required.
Industry Experience
A minimum of 15 years of progressive experience in the biotechnology or pharmaceutical industry, with a significant portion of that time spent in a leadership capacity.
Oncology Expertise
Deep and extensive experience in oncology is mandatory. A proven track record of successfully contributing to the development and approval of oncology therapeutics is highly desired.
Leadership Experience
At least 8-10 years of direct management experience, with demonstrated success in building, leading, and mentoring high-caliber data science and biostatistics teams. Experience managing managers is a plus.
Regulatory Acumen
Extensive experience with global regulatory submissions (NDA/BLA/MAA) and direct interaction with health authorities (FDA, EMA). A thorough understanding of GCP, ICH guidelines, and other relevant regulations is essential.
Technical Proficiency
Expert knowledge of advanced statistical methodologies used in clinical trials. Proficiency with statistical software such as R, Python, and/or SAS.
Preferred Qualifications & Personal Attributes:
- Demonstrated experience in implementing innovative trial designs (e.g., adaptive, basket, umbrella trials).
- Experience with leveraging Real-World Data (RWD) and Real-World Evidence (RWE) in a clinical development and regulatory context.
- Familiarity with the application of AI/ML methodologies to clinical and biomarker data.
- Exceptional strategic thinking and problem-solving skills, with the ability to navigate ambiguity and complexity.
- Outstanding communication skills (both written and verbal), with a proven ability to influence and build consensus among diverse stakeholders, from PhD scientists to executive leadership.
- A collaborative and team-oriented mindset, with a strong sense of urgency and a passion for the company’s mission.
Benefits & Perks Offered
Our client believes in investing in their people and offers a highly competitive and comprehensive benefits package designed to support the well-being and professional growth of their employees. As a key leader, you can expect:
Competitive Compensation
A highly attractive base salary, annual performance-based bonus, and a significant long-term incentive package (stock options/equity) that aligns your success with the company’s growth.
Comprehensive Health and Wellness
Premium medical, dental, and vision insurance plans for you and your dependents, along with wellness programs and resources.
Retirement Planning
A robust 401(k) plan with a generous company match to help you plan for your future.
Work-Life Balance
A generous paid time off (PTO) policy, including vacation, sick leave, and company-paid holidays, to ensure you have time to rest and recharge.
Relocation Support
A comprehensive relocation package is available for the ideal candidate to facilitate a smooth transition to the Raleigh, NC area.
Professional Development
A strong commitment to your growth, with support for attending industry conferences, pursuing further training, and staying at the cutting edge of your field.
Impactful Culture
The opportunity to work in a dynamic, mission-driven, and collaborative environment where your contributions will have a direct and meaningful impact on the lives of patients.
How to Apply
If you are a visionary data science leader with a passion for oncology and a desire to make a significant impact in a growing biotech company, we want to hear from you. This is a unique opportunity to shape the future of cancer therapy from a key leadership position.
To be considered for this confidential search, please submit your resume and a cover letter outlining your qualifications and interest in the role. JRG Partners is the exclusive recruitment partner for this position. All applications will be treated with the strictest confidence.
