NGS Lab Manager Genetics and Genomics – San Diego, CA

Are you a skilled scientific leader passionate about advancing genetics and genomics through next-generation sequencing (NGS) technologies? We are seeking an experienced NGS Lab Manager to oversee and optimize operations in a state-of-the-art genomics laboratory based in San Diego, CA. This role offers a unique opportunity to lead innovative research initiatives, ensure lab excellence, and drive impactful discoveries in the field of genetics.

Manage a Premier Genomics Laboratory with Impact

Join a pioneering genetics and genomics organization in San Diego committed to pushing the boundaries of scientific knowledge. As the NGS Lab Manager, you will leverage your expertise in sequencing technologies and laboratory management to ensure high-quality data production, workflow efficiency, and compliance with regulatory standards. If you thrive in a collaborative environment and excel at mentoring technical teams, this position allows you to shape the future of genomic science and its applications.

Key Responsibilities of the NGS Lab Manager – Genetics and Genomics

Laboratory Leadership & Management:
Oversee daily operations of the next-generation sequencing (NGS) laboratory, ensuring efficient workflow, high-quality data generation, and timely project delivery. Manage lab personnel, including training, scheduling, and performance evaluation to foster a productive and collaborative environment.

NGS Workflow Optimization:
Develop, implement, and continuously improve protocols for sample preparation, sequencing, and data analysis. Ensure laboratory processes adhere to best practices and cutting-edge technologies to maximize throughput and accuracy.

Quality Control & Assurance:
Maintain rigorous quality control standards across all sequencing activities. Troubleshoot technical issues, validate new assays and platforms, and ensure compliance with regulatory and accreditation requirements.

Project Coordination & Collaboration:
Work closely with research scientists, bioinformaticians, and external collaborators to support genomics projects. Manage timelines, resources, and communication to facilitate smooth execution from sample receipt to data delivery.

Data Integrity & Documentation:
Ensure comprehensive documentation of laboratory procedures, sequencing runs, and maintenance activities. Oversee data management practices that guarantee accuracy, reproducibility, and secure storage of sensitive genomic information.

Equipment & Resource Management:
Supervise maintenance, calibration, and procurement of NGS instruments and lab supplies. Evaluate emerging technologies and recommend investments to enhance lab capabilities and efficiency.

Regulatory Compliance & Safety:
Ensure the lab operates in full compliance with institutional, local, and federal regulations governing clinical and research genomics. Promote laboratory safety standards and implement training programs for all staff.

Team Development & Mentorship:
Recruit, mentor, and develop laboratory staff to build a high-performing team. Foster a culture of continuous learning, innovation, and scientific excellence within the lab environment.

What the Client is Looking for in You

The client is seeking a highly skilled and proactive NGS Lab Manager with deep expertise in genetics and genomics, coupled with strong leadership abilities to manage a cutting-edge next-generation sequencing laboratory. You should be an adaptable, detail-oriented professional who thrives in a fast-evolving scientific environment and is committed to driving excellence in genomics research and lab operations.

Proven Expertise in Next-Generation Sequencing and Genomics
The ideal candidate will have substantial hands-on experience with NGS technologies, including sample preparation, sequencing workflows, and data quality control. You should demonstrate a strong understanding of genetic and genomic applications in both research and clinical contexts, with a track record of successfully managing complex sequencing projects.

Strong Leadership and Team Management Skills
The client wants a leader who can effectively manage and mentor laboratory staff, fostering a culture of collaboration, precision, and innovation. Experience in recruiting, training, and developing high-performing scientific teams is highly valued, as is the ability to drive operational efficiency and accountability.

Strategic and Analytical Thinker
You must be capable of optimizing lab workflows and resource allocation while maintaining the highest quality standards. The ideal candidate will have experience implementing new protocols and technologies, solving technical challenges, and continuously improving lab performance in a goal-oriented manner.

Commitment to Quality, Compliance, and Safety
The client expects strict adherence to regulatory guidelines and institutional policies governing genomics laboratories. You should have a strong commitment to maintaining laboratory safety, ensuring data integrity, and meeting compliance requirements to support research and clinical goals.

Excellent Communication and Collaboration Abilities
As NGS Lab Manager, you will work closely with scientists, bioinformaticians, clinicians, and external partners. The ability to communicate technical concepts clearly, coordinate cross-functional projects, and build strong professional relationships is essential.

Innovative Mindset with a Focus on Scientific Excellence
The client values candidates who stay abreast of emerging genomic technologies and industry trends, applying innovative solutions to advance the laboratory’s capabilities. A passion for scientific discovery and continuous learning will set you apart.

FAQs About the Role – NGS Lab Manager Genetics and Genomics

1. What are the key responsibilities of the NGS Lab Manager in this role?
As the NGS Lab Manager, you will oversee the daily operations of the next-generation sequencing laboratory, ensuring high-quality data production and efficient workflow. You will manage lab personnel, maintain equipment, implement and optimize sequencing protocols, and ensure compliance with safety and regulatory standards. Collaboration with research teams and stakeholders to support genomics projects is also a core responsibility.

2. What qualifications and experience are required for this position?
The ideal candidate should have strong expertise in next-generation sequencing technologies and genetics/genomics research. Experience managing a genomics lab or similar scientific facility is essential. A degree in molecular biology, genetics, bioinformatics, or a related field is required; advanced degrees (Master’s or PhD) are preferred. Proven experience with laboratory management, quality control, and regulatory compliance is highly valued.

3. What leadership qualities are essential for this role?
The client seeks a detail-oriented, organized, and collaborative leader who can effectively manage and mentor lab staff. Strong communication skills, problem-solving abilities, and the capacity to coordinate cross-functional teams are key. You should demonstrate a commitment to scientific excellence, quality assurance, and continuous improvement.

4. What challenges can I expect in this role?
Challenges include managing rapidly evolving sequencing technologies, troubleshooting technical issues, maintaining stringent quality standards, and ensuring timely project delivery. Balancing resource allocation, staff development, and compliance with regulatory requirements also requires adaptability and proactive management.

5. How does this role contribute to the organization’s scientific goals?
The NGS Lab Manager plays a critical role in enabling high-quality genomics data generation that underpins research and clinical applications. Your leadership ensures that sequencing projects run smoothly, data integrity is maintained, and innovations in genomic technology are effectively integrated, accelerating scientific discovery.

6. What is the work environment and culture like in the genomics lab?
The lab fosters a collaborative, innovation-driven culture focused on scientific rigor and continuous learning. It is a fast-paced environment where teamwork, accountability, and adaptability are highly valued. You will have opportunities to engage with multidisciplinary teams and contribute to cutting-edge genomics research.

What Remuneration Can You Expect from This Job?

As the NGS Lab Manager in Genetics and Genomics based in San Diego, CA, you can expect a competitive compensation package designed to attract highly qualified scientific leaders with expertise in next-generation sequencing and laboratory management. The remuneration for this role typically includes:

1. Base Salary
The base salary for an NGS Lab Manager varies depending on the size of the organization, complexity of the lab, and level of experience. Generally, annual salaries range from $90,000 to $140,000, with larger research institutions or biotech companies offering salaries at the higher end of this scale.

2. Performance-Based Incentives
In addition to a base salary, performance bonuses may be offered based on laboratory productivity, project milestones, data quality metrics, and overall team performance. These incentives can range from 5% to 15% of the base salary.

3. Benefits Package
Comprehensive benefits often include:

Health, dental, and vision insurance
Retirement plans such as 401(k) with employer contributions
Paid time off and holidays
Professional development support including conference attendance and training

4. Opportunities for Career Growth and Development
Many organizations offer career advancement pathways and professional growth opportunities that may include salary increases, leadership bonuses, and expanded responsibilities, tied to demonstrated success and innovation in the lab.

5. Additional Perks
Depending on the employer, additional perks may include flexible work arrangements, relocation assistance for candidates moving to San Diego, wellness programs, and employee stock purchase plans for biotech firms.

Total Compensation Outlook

Taking all factors into account—base salary, incentives, and benefits—the total compensation package for the NGS Lab Manager role is competitive within the biotech and genomics sector and designed to reward technical excellence, leadership, and contribution to advancing genomic science.

How to Apply

If you are an experienced and detail-oriented leader with a strong background in next-generation sequencing, genetics, and genomics laboratory management, we invite you to apply for the NGS Lab Manager position in San Diego, CA. This is a unique opportunity to lead cutting-edge genomics operations, support impactful research, and drive innovation in a collaborative scientific environment.

To apply, please submit your resume along with a cover letter outlining your expertise in NGS technologies, lab management, quality control, team leadership, and your experience ensuring regulatory compliance. Highlight your ability to optimize sequencing workflows, manage personnel, and contribute to advancing genomics research initiatives.

This role offers a meaningful career path where you will play a critical role in shaping the success of genomics projects and laboratory excellence. Apply today to take the next step in your scientific leadership career as NGS Lab Manager in San Diego, CA!

For more information or to explore similar opportunities, please visit our Genetics and Genomics Recruiting page.

Job Category: Genetics and Genomics

Job Type: Full Time

Job Location: San Diego

NGS Lab Manager Genetics and Genomics – San Diego, CA